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Anti-obesity medication or weight loss drugs are all pharmacological agents that reduce or control weight. Rimonabant (Acomplia), a second drug, works via a specific blockade of the endocannabinoid system. Many of these tainted products are imported, sold online, and heavily promoted on social media sites. Appetite suppression- Catecholamines and their derivatives (such as phentermine and other amphetamine -based drugs) are the main tools used for this, although other classes of drugs such as anti-depressants and mood stabilizers have been anecdotally used for appetite suppression (see: bupropion and topiramate ). In addition, FDA maintains an online list of tainted weight-loss products. But just because you see a supplement product on a store shelf does not mean it is safe, Humbert says. This remained the mainstay of treatment for well over a thousand years. Overdose, although rare, lead to a rise in body temperature and, ultimately, fatal hyperthermia. This was a combination of multiple pills, all thought to help with weight loss, taken throughout the day. Orlistat (Xenical) the most commonly used medication to treat obesity and sibutramine (Meridia) a medication that was recently withdrawn due to cardiovascular side effects. The first described attempts at producing weight loss are those of Soranus of Ephesus, a Greek physician, in the second century AD. Get Consumer Updates by E-mail Consumer Updates RSS Feed. Current and potential anti-obesity drugs may operate through one or more of the following mechanisms. The OTC fiber supplements glucomannan and guar gum have been used for the purpose of inhibiting digestion and lowering caloric absorption.
He prescribed elixirs of laxatives and purgatives, as well as heat, massage, and exercise. Most recently, FDA has found a number of products marketed as dietary supplements containing fluoxetine, the active ingredient found in Prozac, a prescription drug marketed for the treatment of depression and other conditions. The agency also has issued warning letters, seized products, and criminally prosecuted people responsible for marketing these illegal diet products. When safety issues are suspected, FDA must investigate and, when warranted, take steps to have these products removed from the market. They worked primarily by suppressing appetite, and had other beneficial effects such as increased alertness. FDA has issued over 30 public notifications and recalled 7 tainted weight loss products in 2014. If you suspect a product marketed as a dietary supplement sold online may be tainted, FDA urges you to report that information online. Worse, they can cause serious harm, say FDA regulators. For example, Orlistat (also known as Xenical and Alli) blocks fat breakdown and thereby prevents fat absorption. FDA has received numerous reports of harm associated with the use of weight loss products, including increased blood pressure, heart palpitations (a pounding or racing heart), stroke, seizure and death. Amphetamines (marketed as Benzedrine) became popular for weight loss during the late 1930s. The most significant side effect was a sensation of warmth, frequently with sweating. It was not until the 1920s and 1930s that new treatments began to appear. Based on its effectiveness for hypothyroidism, thyroid hormone became a popular treatment for obesity in euthyroid people.
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